منابع مشابه
Topiramate for migraine prophylaxis.
Topiramate is a neurmodulatory compound with neuron stabilizing properties and is approved for the preventive treatment of migraine in several countries [5]. Several small and large trials have reported good efficacy and safety of topiramate in migraine prophylaxis in adults [6]. The present study was done to study the role of topiramate in migraine prophylaxis in children who either failed to ...
متن کاملThe Efficacy and Safety of Topiramate for Prophylaxis of Migraine in Children
OBJECTIVE Migraine is the most common acute intermittent primary headache in children and prophylactic therapy is indicated in children with frequent or disabling headaches. The purpose of this study was to evaluate the efficacy and safety of topiramate (TPM) for migraine prophylaxis in children. MATERIALS & METHODS In a quasi-experimental study, monthly frequency, severity and duration of he...
متن کاملTopiramate: Safety and Efficacy of its Use in the Prevention and Treatment of Migraine
Migraine headaches are typically episodic in nature and may affect nearly 10% of the population. In addition to treatment, prevention of subsequent episodes or progression to a chronic migraine state is an important therapeutic area. Topiramate is a centrally acting medication approved for both the prevention of seizures and migraine headache. At this time, the exact mechanism of how topiramate...
متن کاملTopiramate in the prevention and treatment of migraine: efficacy, safety and patient preference
Migraine is a very common disorder characterized by the combination of typical headache with associated autonomic symptoms and/or the presence of aura. Considerable advances have been made in recent years to understand the pathophysiology of migraine, which has led to improved treatment options for the acute migraine attack as well as migraine prophylaxis. Unfortunately, preventive treatment is...
متن کاملTopiramate--safety and tolerability.
Topiramate is a new novel drug for the treatment of intractable seizures that is to be used in an adjunctive fashion. A review of the seven double-blind controlled studies was undertaken with special attention paid to safety and tolerability data. The studies were similar in design but used varying doses of the drug. To date there has been no evidence of serious systemic side effects such as ra...
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ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2013
ISSN: 0975-1483
DOI: 10.1016/j.jyp.2012.12.001